PGDH18

Population Genetics and Demographic History:
model-based approaches

PGDH18 Population Genetics and Demographic History
Mon, May 14th
Coalescent theory - Day #1
09:30 - 11:00 Introductions and expectations.
Wright-Fisher model and Kingman's coalescent.
11:00 - 11:30 Coffee Break
11:30 - 12:30 Coalescent simulations using ms.
12:30 - 14:00 Lunch Break
14:00 - 16:00 Introduction to the R statistical language (Quick Recap).
16:00 - 16:30 Tea Break
16:30 - 18:00 Coalescent simulations and tree visualizations using R packages.
Tue, May 15th
Demographic Inference in Population Genetics 1 - Day#2
09:30 - 11:00 Morning Wrap-up (what have we done so far?
The Sequentially Markovian Coalescent. Introduction to FastSimCoal.
11:00 - 11:30 Coffee Break
11:30 - 12:30 The PSMC: reconstructing population size changes based on one diploid genome.
12:30 - 14:00 Lunch Break
14:00 - 16:00 Fast SimCoal and the Site Frequency Spectrum (SFS) 1
16:00 - 16:30 Tea Break
16:30 - 18:00 Fast SimCoal and the Site Frequency Spectrum (SFS) 2
Wed, May 16th
Demographic Inference in Population Genetics 2 - Day#3
09:30 - 11:00 Morning Wrap-up (what have we done so far?
ABC (Approximate Bayesian Computation) in pop genetics and pop genomics.
11:00 - 11:30 Coffee Break
11:30 - 12:30 ABC (Approximate Bayesian Computation) in pop genetics and pop genomics.
12:30 - 14:00 Lunch Break
14:00 - 16:00 ABC (Approximate Bayesian Computation) in pop genetics and pop genomics
16:00 - 16:30 Tea Break
16:30 - 18:00 Simulating populations in space with the SINS software (I).
Thu, May 17th
Influence of population structure on the demographic inference - Day#4
09:30 - 11:00 Morning Wrap-up (what have we done so far?)
Simulating populations in space with the SINS software (II).
11:00 - 11:30 Coffee Break
11:30 - 12:30 Discussion of SINS Results.
12:30 - 14:00 Lunch Break
14:00 - 16:00 Signals of population size changes in structured populations.
16:00 - 16:30 Tea Break
16:30 - 18:00 Introduction of the Inverse Instantaneous Coalescence Rate (IICR).
Fri, May 18th
Demographic history with genomic data - Day#5
09:30 - 11:00 Morning Wrap-up (what have we done so far?
The IICR as a guide to demographic inference and model exclusion/choice (I).
11:00 - 11:30 Coffee Break
11:30 - 12:30 The IICR as a guide to demographic inference and model exclusion/choice. (II).
12:30 - 14:00 Lunch Break
14:00 - 16:00 Wrap Up on Demographic history and genomic data.
16:00 - 16:30 Tea Break
16:30 - 18:00 Final Discussion / Course Wrap Up.
Course Homepage

Instituto Gulbenkian de Ciência,

Apartado 14, 2781-901 Oeiras, Portugal

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Last updated:   May 10th 2018