Fatima Al-Shahrour is the head of the Bioinformatics Unit at Spanish National Cancer Research Centre (CNIO, Madrid, Spain). She has extensive experience in the study of cancer under a genomic perspective. Her research focuses on applying and developing computational methods to precision medicine, for the interpretation of cancer genomes, drug repositioning and prediction of anticancer therapies. Her group belongs to the National Bioinformatics platform and ELIXIR-ES as a node (https://inb-elixir.es/) and it participates in the ISCIII IMPaCT-Data project. She is also co-director of the Master in Bioinformatics Applied to Personalized Medicine and Health (INS-ISCIII) (https://masterbioinformatica.com/). She obtained her PhD from Universidad Autónoma de Madrid (UAM) in 2006. During her PhD she worked at the Bioinformatics Unit at CNIO and Centro de Investigación Príncipe Felipe Valencia, CIPF (Valencia, Spain) under Joaquín Dopazo's supervision. During this period, her research work dealt with the development of new Bioinformatics tools for microarray gene expression analysis, with a particular focus on computational methods for the functional interpretation of high-throughput experiments. In 2007, she joined the Computational Biology and Bioinformatics group at Cancer Program under supervision of Jill P. Mesirov at the Broad Institute (Cambridge, USA). Her project was focusing mainly in the development of a computational methodology for identifying molecular signatures of oncogenes and tumor suppressor genes based on gene expression data. In 2008, she got a staff position at Broad Institute and Bringham Women Hospital (BWH) as a Computational Biologist working at Benjamin L. Ebert’s lab. During this period, her research was focused on the study of the biology and treatment of cancer under a genomic perspective using hematopoiesis as a model system. After four years at the Broad Institute and BWH, in 2012 she joined the CNIO to lead the Translational Bioinformatics Unit in the Clinical Research and Structural Biology and Biocomputing Programmes. In 2017, she got a permanent position at CNIO and she leads the Bioinformatics Unit at CNIO. As a result of her scientific career, Fatima has published 96 peer-reviewed articles in bioinformatics and cancer genomics fields.

Affiliation: Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, ES

Elena Piñeiro obtained her MSc in Bioinformatics and Computational Biology from Universidad Complutense de Madrid (UCM) in 2012, working since then as a bioinformatician in the Translational Bioinformatics Unit, and then, in the Bioinformatics Unit at CNIO. Her work was mainly focused on the elaboration and execution of workflows for the analysis and prioritization of genomic variation obtained from NGS technologies. In 2021 she obtained her PhD in Molecular Biosciences from Universidad Autónoma de Madrid (UAM) with the study on methodologies for the in silico drug prescription in precision oncology based on genomics data.

Affiliation: Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, ES

Maria José Jimenez got her MSc in Bioinformatics and Computational Biology at the Universidad Autónoma de Madrid. In 2018 she joined the Bioinformatics Unit to complete her master’s thesis, which was focused in detecting germinal variants associated with adverse drug reactions in order to improve PanDrugs, our personalized drug prescription tool for cancer patients. Then, she stayed at BU in order to pursue her PhD, which aims to explore tumor clonality and how it can be tackled therapeutically.

Affiliation: Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, ES