SG09 Structural Genomics |
IMPORTANT DATES for SG09
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Instructors: |
Marc A. Marti-Renom has 14 years of experience in international academic institutions. Since July 2006 Head of the Structural Genomics Unit at the CIPF, Valencia (Spain). He obtained his Ph.D. in January 1999 under the supervision of Profs. Martin Karplus, Francesc X. Aviles, and Baldomero Oliva. He was Postdoctoral Fellow and Research Associate at the Rockefeller University (1999-2003). Assistant Adjunct Professor at the University of California at San Francisco (2003-2006). Key personnel in three funded NIH grants. Member of the Admissions Committee at the School of Pharmacy at UCSF (2003-2006). Up-to-date, his research has resulted in 39 peer-reviewed articles, 2 invited reviews, 9 book chapters and 12 invited presentations in international conferences. He has directed the development of two major software packages (EVA-CM and DBAli) as well as has significantly contributed to the MODBASE, MODPIPE and MODELLER software packages. Detailed information about his research can be found at http://sgu.bioinfo.cipf.es. Centro de Investigación Príncipe Felipe. Valencia. Spain. |
Antonio Pineda-Lucena got his
PhD at the Centro de Investigaciones Biologicas (CSIC, Madrid, Spain) in 1995. After that, he moved to the Netherlands (EMBO and Marie Curie fellowships) to work as a postdoctoral researcher with Prof. Dr. Cees Hilbers at the University of Nijmegen. Later on, he got a position as
an Associate Scientist at the Ontario Cancer Institute in Toronto (Canada), the canadian reference centre for cancer treatment, where he was working in the structural characterization of oncoproteins and tumor suppressors, as well as in the development of new technologies for structural genomics. Two years later, he accepted a position in one of the biggest pharmaceutical companies, AstraZeneca (Manchester, UK). APL joined the Centro de Investigacion Principe Felipe (CIPF) in February, 2005 to head the Laboratory of Structural Biology and the NMR facility. The group has three other members (a Ramon y Cajal senior researcher, three postdoctoral researchers and a technician), with experience in NMR, organic chemistry, cell biology, microbiology, protein chemistry, computational chemistry, cheminformatics and drug design using fragment-based screening.
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Course description:
Structure determination and prediction (days 1 and 2), human variability and pharmacogenomics (day 3), docking of small molecules from an experimental and computational perspective (day 4) and quantitative structure-activity relationships (day 5). |
Course Pre-requisites: Basic Molecular Biology. Elementary computing skills. |
Detailed Program |
Instituto Gulbenkian de Ciência, Apartado 14, 2781-901 Oeiras, Portugal Last updated: June 18th 2009 |