ICG10

Intyegrative Cancer Genomics

Course Timetable (provisional)
ICG10 Integrative Cancer Genomics
Mon, Nov 8th
Day #1
09:30 - 11:00 Introduction to Cancer genetics and genomics

11:00 - 11:30 Coffee Break
11:30 - 12:30 Introduction to genome-wide technologies and their application in cancer
- Array-based technologies
- Next generation sequencing technologies
12:30 - 14:00 Lunch Break
14:00 - 16:00 IntOGen
- Introduction
- Exploring IntOGen data (hands on)
16:00 - 16:30 Tea Break
16:30 - 18:00 The International Cancer Genome Project and The Cancer Genome Atlas
-Projects design and principals
- Exploring ICGC data (hands on)
Tue, Nov 9st
Day #2
09:30 - 11:00 Integrative data analysis 1
Analysis of high-throughput data:
Enrichment analysis, identification of driver alterations, statistical combination of information from heterogeneous data sources.
11:00 - 11:30 Coffee Break
11:30 - 12:30 Gitools introduction and hands on
- Introduction
- Enrichment analysis with oncomodules
- Combinations
- OncoDrive
12:30 - 14:00 Lunch Break
14:00 - 16:00 Cancer genomics resources
- Oncomine
- COSMIC UCSC cancer genomics browser
- Integrative Genomics Viewer
16:00 - 16:30 Tea Break
16:30 - 18:00 IntOGen and Gitools hands on 1
Exploring the similarities and differences between the alteration patterns of different tumor types
Wed, Nov 10th
Day #3
09:30 - 11:00 Integrative data analysis 2
Integration of information from different alteration types:
- correlations (GiTools)
- supervised/unsupervised methods for subtype discovery and classification
11:00 - 11:30 Coffee Break
11:30 - 12:30 Integrative data analysis 2
-Integration of information from different alteration types: correlations (GiTools)
- supervised/unsupervised methods for subtype discovery and classification
12:30 - 14:00 Lunch Break
14:00 - 16:00 Integrative data analysis 2 practical
- Integration with clinical data (clustering, chi square, ...)
- Survival analysis: survival curves
- Integrative analysis with Mev
16:00 - 16:30 Tea Break
16:30 - 18:00 Review of recent integrative cancer genomics studies
We will review some recent case studies involving integrative oncogenomics analysis to show the usefulness of the approach
Wrap up
Course Homepage

Instituto Gulbenkian de Ciência,

Apartado 14, 2781-901 Oeiras, Portugal

GTPB Homepage

IGC Homepage

Last updated:   July 30th 2010