Structural Genomics and Drug Design

Marc A. Marti-Renom After obtaining his PhD at the Universitat Autónoma de Barcelona in January 1999, under the supervision of Profs. Martin Karplus, Francesc X. Avilés, and Baldomero Oliva, he moved to the Rockefeller University (New York, USA) were he was the recipient of the Burroughs Wellcome Fund fellowship for interdisciplinary research in physics, chemistry, and computation. Between 2002 and 2003 he was promoted to Research Associate at the Rockefeller University and then, in February 2003, appointed as Assistant Adjunct Professor by the University of California at San Francisco. During his time at the UCSF he was key personnel in three funded NIH grants. Between 2003 and 2007, he has also served as member of the Admissions Committee at the School of Pharmacy (UCSF). Since 2002 he has given invited presentations in more than 30 international conferences, and regularly taught comparative modeling. Up to now, his research has resulted in 50 peer-reviewed articles, and 10 book chapters or invited reviews. He has also played a leader role for a large number of projects, which included the design and development of two major software packages (EVA-CM and DBAli) as well as has significantly contributed to the MODBASE, MODPIPE, MODELLER and IMP packages. He has taught Structural Genomics in GTPB twice before.

Antonio Pineda-Lucena got his PhD at the Centro de Investigaciones Biologicas (CSIC, Madrid, Spain) in 1995. After that, he moved to the Netherlands (EMBO and Marie Curie fellowships) to work as a postdoctoral researcher with Prof. Dr. Cees Hilbers at the University of Nijmegen. Later on, he got a position as an Associate Scientist at the Ontario Cancer Institute in Toronto (Canada), the canadian reference centre for cancer treatment, where he was working in the structural characterization of oncoproteins and tumor suppressors, as well as in the development of new technologies for structural genomics. Two years later, he accepted a position in one of the biggest pharmaceutical companies, AstraZeneca (Manchester, UK). APL joined the Centro de Investigacion Principe Felipe (CIPF) in February, 2005 to head the Laboratory of Structural Biology and the NMR facility. The group has three other members (a Ramon y Cajal senior researcher, three postdoctoral researchers and a technician), with experience in NMR, organic chemistry, cell biology, microbiology, protein chemistry, computational chemistry, chemical compound analysis and drug design using fragment-based screening. He has taught Structural Genomics in GTPB twice before.
Centro de Investigación Príncipe Felipe. Valencia. Spain.

Basic Molecular Biology. Elementary computing skills.