RNA Bioinformatics

   Deadline for applications: May 11th 2012
   Notification of acceptance dates:
        EARLY: April 28th 2012
        NORMAL: May 12th 2012
   Course date: May 15th - May 17th 2012


Lars Barquist completed a bachelor's degree in Biomathematics at Rutgers University in New Brunswick, New Jersey, USA. Following this, he spent two years as a specialist in the Department of Bioengineering at the University of California, Berkeley working on problems in biological sequence analysis. He is currently pursuing a PhD at the Wellcome Trust Sanger Institute and the University of Cambridge.

Wellcome Trust Sanger Institute, Hinxton, UK

Anton Enright completed his PhD degree at the Computational Genomics Group in the EBI on modelling protein interactions. He then worked as a post-doc at the Computational Biology Center in the Memorial Sloan-Kettering Cancer Center before taking a group leader position at the The Wellcome Trust Sanger Institute. He is now a group leader at the EBI.

European Bioinformatics Institute, Hinxton, UK

Additional Guest Instructors:   Afonso Guerra-Assunção (EBI) and Francisco Enguita (IMM)

Course description:


This course will give an overview of RNA and the informatic challenges associated with studying RNA. It will be run as a mixture of lectures and hands-on problem solving sessions.


This course is practical in nature. We will introduce RNA secondary structure prediction, state of the art RNA homology search tools, methods for predicting RNA:RNA interactions, and comparative methods for studying RNA sequence and structure. After participating attendees will be able to use current methods and be aware of limitations in RNA informatics. In addition we will cover recent advances in high-throughput methods for discovering and characterizing small RNAs, including Piwi-interacting RNAs and microRNAs. This will include an introduction to processing size-selected RNA-seq data, microRNA target prediction using microarrays and Sylamer, and CLIP-Seq.

Course Pre-requisites:

Basic Molecular Biology. Graduate level understanding of Molecular Biology. A basic level of computer knowledge will be assumed.

Target Audience:

Biologists interested in applying computational tools for RNA sequence analysis to their research.

Detailed Program

In collaboration with INTERBIO

Sponsorship available for members of the following INTERBIO Nodes:
- Université Paul Sabatier Toulouse - UPS (Midi-Pyrénées - France) (www.ups-tlse.fr)
- Fundación Privada BioRegió de Catalunya - BIOCAT (Catalonia - Spain), (www.biocat.cat)
- Institut Européen de Chimie et Biologie - IECB (Aquitaine - France), (www.iecb.u-bordeaux.fr)
- Fundación de la Comunidad Valenciana para la Innovación Urbana y Economía del Conocimiento - FIVEC (Valencia - Spain), (www.fivec.org).

If you wish to apply as a member of one of these institutions, please contact your local INTERBIO representative.

Instituto Gulbenkian de Ciência,

Apartado 14, 2781-901 Oeiras, Portugal

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Last updated:  May 4th 2012