CSDM14

GTPB: Chromosome structure determination using modelling and Hi-C data

Course Timetable (provisional)
3DMOG14 3D modeling of genomes and genomic domains
Tue, Nov 25th
Day #1
09:30 - 10:00 Welcome and introductions
10:00 - 11:00 3D modeling of genomes and genomic domains: an overview
11:00 - 11:30 Coffee Break
11:30 - 12:30 Next Generation Sequencing (NGS), 3C-like data and chromatin
12:30 - 14:00 Lunch Break
14:00 - 15:00 Chromatin structure and Hi-C data
15:00 - 16:00 Introduction to Linux and Python. The Python notebook
16:00 - 16:30 Tea Break
16:30 - 18:00 From raw data to Hi-C contact matrices
Wed, Nov 26th
Day #2
09:30 - 11:00 Introduction to structure determination
11:00 - 11:30 Coffee Break
11:30 - 12:30 Integrative modeling applied to chromatin
12:30 - 14:00 Lunch Break
14:00 - 16:00 Biological applications
16:00 - 16:30 Tea Break
16:30 - 18:00 Hi-C contact matrices: filtering and normaliztion
Thu, Nov 27th
Day #3
09:30 - 11:00 Integrative modeling applied to chromatin
11:00 - 11:30 Coffee Break
11:30 - 12:30 Biological applications (II)
12:30 - 14:00 Lunch Break
14:00 - 16:00 Introduction to TADbit: installation, testing and system requirements
16:00 - 16:30 Tea Break
16:30 - 18:00 Topologically Associated Domains detection and analysis
Fri, Nov 28th
Day #4
09:30 - 11:00 Biological applications (III)
11:00 - 11:30 Coffee Break
11:30 - 12:30 3D Modeling of real Hi-C data with TADbit (I)
12:30 - 14:00 Lunch Break
14:00 - 16:00 3D Modeling of real Hi-C data with TADbit (II)
16:00 - 16:30 Tea Break
16:30 - 18:00 Analysis of the results

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Instituto Gulbenkian de Ciência,

Apartado 14, 2781-901 Oeiras, Portugal

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