CSDM14
GTPB: Chromosome structure determination using modelling and Hi-C dataCourse Timetable (provisional) |
3DMOG14 | 3D modeling of genomes and genomic domains |
Tue, Nov 25th |
Day #1
|
09:30 - 10:00 | Welcome and introductions |
10:00 - 11:00 | 3D modeling of genomes and genomic domains: an overview |
11:00 - 11:30 | Coffee Break |
11:30 - 12:30 | Next Generation Sequencing (NGS), 3C-like data and chromatin |
12:30 - 14:00 | Lunch Break |
14:00 - 15:00 | Chromatin structure and Hi-C data |
15:00 - 16:00 | Introduction to Linux and Python. The Python notebook |
16:00 - 16:30 | Tea Break |
16:30 - 18:00 | From raw data to Hi-C contact matrices |
Wed, Nov 26th |
Day #2
|
09:30 - 11:00 | Introduction to structure determination |
11:00 - 11:30 | Coffee Break |
11:30 - 12:30 | Integrative modeling applied to chromatin |
12:30 - 14:00 | Lunch Break |
14:00 - 16:00 | Biological applications |
16:00 - 16:30 | Tea Break |
16:30 - 18:00 | Hi-C contact matrices: filtering and normaliztion |
Thu, Nov 27th |
Day #3
|
09:30 - 11:00 | Integrative modeling applied to chromatin |
11:00 - 11:30 | Coffee Break |
11:30 - 12:30 | Biological applications (II) |
12:30 - 14:00 | Lunch Break |
14:00 - 16:00 | Introduction to TADbit: installation, testing and system requirements |
16:00 - 16:30 | Tea Break |
16:30 - 18:00 | Topologically Associated Domains detection and analysis |
Fri, Nov 28th |
Day #4
|
09:30 - 11:00 | Biological applications (III) |
11:00 - 11:30 | Coffee Break |
11:30 - 12:30 | 3D Modeling of real Hi-C data with TADbit (I) |
12:30 - 14:00 | Lunch Break |
14:00 - 16:00 | 3D Modeling of real Hi-C data with TADbit (II) |
16:00 - 16:30 | Tea Break |
16:30 - 18:00 | Analysis of the results |
Course Homepage |
Instituto Gulbenkian de Ciência, Apartado 14, 2781-901 Oeiras, Portugal |