PHSMCP15

Promoter hunting and systems modelling of cellular pathways

Timetable (provisional)
PHSMCP15 Promoter hunting and systems modelling of cellular pathways
Wed, Apr 22nd
Day #1
09:30 - 11:00 Introduction.
Code: Principles of gene regulatory code
11:00 - 11:30 Coffee Break
11:30 - 12:30 Factors: Transcription factor classification. DNA binding domains. TRANSFAC.
12:30 - 14:00 Lunch Break
14:00 - 16:00 Motifs: De-novo identification of DNA motifs
16:00 - 16:30 Tea Break
16:30 - 18:00 Genome Databases
Thu, Apr 23rd
Day #2
09:30 - 11:00 Morning Wrap-up (what have we done so far?)
Enhancers: Site combinations, chromatin and disease enhancers
11:00 - 11:30 Coffee Break
11:30 - 12:30 Networks: Reconstruction of gene regulatory networks
12:30 - 14:00 Lunch Break
14:00 - 16:00 Key-nodes: From motifs to master regulators
16:00 - 16:30 Tea Break
16:30 - 18:00 Targets: Topological analysis of pathways and search for key nodes / drug targets
Fri, Apr 24th
Day #3
09:30 - 11:00 Morning Wrap-up (what have we done so far?)
Systems: Introduction to Mathematical Modeling of Biological Systems.
11:00 - 11:30 Coffee Break
11:30 - 12:30 Modelling1: Mathematical Modeling of Pathway models using CellDesigner, BioUML/geneXplain
12:30 - 14:00 Lunch Break
14:00 - 16:00 Modelling2: Mathematical Modeling of Biological Systems in Practice using Copasi and PyBioS
16:00 - 16:30 Tea Break
16:30 - 18:00 Design: Application of promoter engineering and systems biology in synthetic biology (design of novel biological systems).
Final wrap-up session
Course Homepage

Instituto Gulbenkian de Ciência,

Apartado 14, 2781-901 Oeiras, Portugal

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Last updated:   Mar 2nd 2015