Bioinformatics for Integrative Genomics

Exploring and making sense of multidimensional data sets that result from merging heterogeneous genomic data resources

   Deadline for applications: October 24th 2011
   Notification of acceptance dates:
        EARLY: October 10th 2011
        NORMAL: October 25th 2011
   Course date: November 7th - November 9th 2011


Sophia Derdak obtained her PhD in immunology from the Medical University of Vienna, Austria, in 2003. After a postdoctoral project at the German Cancer Research Center (Heidelberg, Germany), she moved to Barcelona to work in cancer biomarker discovery at Oryzon Genomics before joining the Biomedical Genomics Group in 2010. She is interested in integrative Omics, personalized genomics and the analysis of Next Generation Sequencing data.

Universitat Pompeu Fabra (UPF), Barcelona, ES

Alba Jené-Sanz is a Biologist from the Universitat Pompeu Fabra. She has a Master in Bioinformatics from the same university and she is currently pursuing a PhD at the Biomedical Genomics Group of the University Pompeu Fabra. Her main interests are the study of regulatory pathways in cancer from an epigenomics point of view, and the use of sequencing technologies for large-scale cancer genomics studies.

Universitat Pompeu Fabra (UPF), Barcelona, ES

Course description:

The application of high-throughput technologies in medical genomics yields complex, multidimensional data sets that describe in detail the myriad changes that occur within individual cells and how these changes differ between patients, cells or conditions. Usually we want to use this data to answer some specific questions. For instance, which of the long list of mutations detected are likely to affect the function of the protein and which are probably neutral? Which of the genes affected by those mutations are already known to be involved in cancer or other diseases? Which pathways or biological processes are affected by the transcriptomic alterations detected in my experiment? Etc.
We need to apply bioinformatic approaches to answer these questions. This course provides theoretical and practical expertise in the field of bioinformatics for integrative genomics. Students are updated on the state of the art in the field and they become capable of handling and analyzing genomics data. Upon completion, the attendees are able to perform integrative analysis and interpret the results, in order to answer specific biological questions.
To achieve these objectives we will extensively use three tools developed in the Biomedical Genomics Group of UPF: IntOGen, Gitools and Condel. We will also explore a large set of web accessible data resources and software.

Note: This course is a slighly modified version of the course with the same name that was held in Barcelona in June 2011 (

Target Audience:

The course is directed to researchers in biology and medicine. Background knowledge in bioinformatics is not necessary.

Course Pre-requisites:

Basic Molecular Biology. Elementary computing skills.

Detailed Program

Instituto Gulbenkian de Ciência,

Apartado 14, 2781-901 Oeiras, Portugal

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Last updated:   September 17th 2011