BIG11

Bioinformatics for Integrative Genomics

Course Timetable
BIG11 Bioinformatics for Integrative Genomics
Mon, Nov 7th
Day #1
09:30 - 10:30Introduction to Integrative Genomics
Course Introduction
General issues in Integrative methods in Biology
10:30 - 11:00 Coffee Break
11:00 - 12:30 Exploring IntOGen data
IntOGen hands-on exercises
12:30 - 14:00 Lunch Break
14:00 - 16:00 Introduction to Enrichment Analysis
Gitools and Enrichment Analysis
16:00 - 16:30 Tea Break
16:30 - 18:00 Performing Enrichment Analysis (EA) using Gitools with IntOGen data
Hands on exercises in Gitools
Introduction to TFBS and GO enrichment analysis
Tue, Nov 8th
Day #2
09:30 - 10:30 Enrichment analysis with Gene Ontology and TFBS
EA with Gitools using microarray datasets hands-on exercises
10:30 - 11:00 Coffee Break
11:00 - 12:30 Identifying significantly altered genes with Oncodrive
Oncodrive
Identify significantly upregulated genes in a cancer microarray experiment hands-on exercise
12:30 - 14:00 Lunch Break
14:00 - 16:00 Compare and combine experiments
Combination of statistical results
Compare and combine results from independent experiments hands-on exercise
16:00 - 16:30 Tea Break
16:30 - 18:00 Clustering, correlations and overlaps of expression patterns among samples or conditions
Clustering, correlations and overlaps with Gitools
Expression profile clustering exercise
Wed, Nov 9th
Day #3
09:30 - 10:30 Correlation of expression patterns among samples or conditions
Expression profile correlations hands-on exercises and discussion
10:30 - 11:00 Coffee Break
11:00 - 12:30 Overlaps of expression patterns among samples or conditions
Overlaps analysis hands-on exercises and discussion
12:30 - 14:00 Lunch Break
14:00 - 16:00 Identifying functional non-synonymous SNVs using Condel
Condel lecture and Condel hands-on exercises
16:00 - 16:30 Tea Break
16:30 - 18:00 Final wrap-up session
Reflections on Integrative methods and their applications
Course Homepage

Instituto Gulbenkian de Ciência,

Apartado 14, 2781-901 Oeiras, Portugal

GTPB Homepage

IGC Homepage

Last updated:   September 18th 2011